NAPLEX Examination.
Practice Question # 101.
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1. Question
Which of the following asthma therapies is effective by decreasing the amounts of released leukotrienes?
Correct
Answer & Explanation:
The correct answer is B
Zafirlukast and montelukast exert their effect by blocking leukotrienes at their receptor. Zileuton, which acts by inhibiting lipo-oxygenase, will decrease the synthesis of these infl ammatory mediators. Th erefore, it is the only drug listed that will decrease the synthesis and, consequently, the release of leukotrienes. Alprostadil and bimatoprost are both prostaglandin analogs.
Incorrect
Answer & Explanation:
The correct answer is B
Zafirlukast and montelukast exert their effect by blocking leukotrienes at their receptor. Zileuton, which acts by inhibiting lipo-oxygenase, will decrease the synthesis of these infl ammatory mediators. Th erefore, it is the only drug listed that will decrease the synthesis and, consequently, the release of leukotrienes. Alprostadil and bimatoprost are both prostaglandin analogs.
