NCLEX Examination.
Practice Question # 803.
nclex examination.
ANTIARTHRITIS AGENTS:
Arthritis is potentially debilitating inflammatory process in the joints that cause pain and bone deformities. Antiarthritis drugs include the gold compounds, which are used to prevent and suppress arthritis in selected patients with rheumatoid arthritis. The other antiarthritis drugs are specifically used to block the inflammation and tissue damage of rheumatoid arthritis
Gold Compounds:
Some patients with rheumatic inflammatory conditions do not respond to the usual anti-inflammatory therapies, and their conditions worsen despite weeks or months of standard pharmacological treatment. Some of these patients respond to treatment with gold salts, also known as chrysotherapy, in which gold is taken up by macrophages, which then inhibit phagocytosis; it is reserved for use in patients who are unresponsive to conventional therapy and can be very toxic. The gold salts available for use include auranofin (Ridaura), aurothioglucose (Solganal), and gold sodium thiomalate (Aurolate).
